How will infrastructure centres be connected?

When formulating a research question or strategy, assessing modelling requirements, experimental designs and available repositories should be done back-to-back, often simultaneously.

Therefore the connections between different parts of a project need to be seamless, fast and transparent, so as to:

  • Provide all possible connections between ISBE centres that will promote European systems biology
  • Provide intuitive interfaces that enable computer assisted connecting
  • Provide ways in which systems biology as a process can be partitioned/integrated over multiple centres

In order to make distributed ISBE nodes interoperable, interactive, efficient, and intuitive, we need to resolve several challenges to ascertain optimal interconnectivity – both physical and virtual – throughout the infrastructure.

More precisely, we aim to establish:

  • Modes to split large systems tasks into modules that can be processed in parallel in separate ISBE centres. The outputs need to subsequently be reintegrated
  • Quality control procedures that are required, especially in the light of task distribution and reintegration
  • Enabling real-time modelling and data integration services, also over multiple centres simultaneously, and provide links to experimental design, data and expertise
  • Ways to standardise inputs and outputs of nodes or modules to allow for automated division/integration through web services
  • Specifications of a suite of systems biology-driven dynamic-integration workflows that allow i) to integrate results from (parts of) separate research projects, and ii) to enable big (community) research programmes of larger, more integral biological entities, being modelled in parts and then assembled